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Laying the foundations for tomorrow's medicine

News

  • Alzheimer's Disease: Therapy must begin early

    Protein plaques in the brain are the cause of Alzheimer's disease and the starting point for possible therapies. At later stages, however, the disease may become independent from them, report HIH researchers

    Read our press release (in German only)

  • "There are many different types of memory"

    In an interview with the Hertie Foundation, Hertie Fellow Dr. rer. nat. Marion Inostroza (Tübingen University Hospital) talks about her research, different types of memory and the perfect conditions for excellent clinical brain research.

    Read the interview here

    Recent publication about the topic

  • All senses aboard - how does tasting work?

    Taste receptors in more than 10,000 taste buds on the tongue react to sweet, sour, salty, bitter and umami, which means spicy or savory. But it's in the brain that we decide whether to swallow what's in our mouths or not. How do we taste in the first place? In the video of the Hertie Foundation (in German only), Dr. Mondino explains the exact process in a self-experiment.

  • New target for Alzheimer's therapies found

    Researchers from Tübingen discover link between the protein medin and Alzheimer's disease

    See press release

    Read a recent interview of the Hertie Foundation with Dr. Jonas Neher, principal investigator of the study (in German only)

  • Citation ranking "Web of Science” lists HIH researchers again

    Professor Ulf Ziemann and Professor Mathias Jucker are among the world's most cited scientists again this year, according to a recent analysis by Clarivate Analytics. Of the world’s population of scientists, highly cited researchers are 1 in 1,000... More information

  • How do brain cells age?

    A Tübingen research project receives 1.6 million US dollars from the Chan Zuckerberg Initiative

    Read our press release

Departments

  • Neurology and Stroke

    The Department of Neurology and Stroke has the main focuses in neurovascular medicine (vessel diseases of the brain, cerebral stroke), neuro-oncology (brain tumors, brain metastases), neuro-immunology (e.g., multiple sclerosis) and neuro-intensive medicine. ...more information

  • Neurodegenerative Diseases

    The Department of Neurodegenerative Diseases treats in-patients on a ward of about 20 beds and in several out-patient clinics. The clinical focus lies on neurodegenerative diseases such as Parkinson’s disease, the ataxias, spastic paraplegias, and dementias. ...more information

  • Neurology and Epileptology

    The Department of Neurology and Epileptology has a focus on epilepsy and other paroxysmal neurological disorders. In these diseases, the excitability of nerve cells temporarily changes either due to genetic or acquired defects. ...more information

  • Department of Neurology and Interdisciplinary Neuro-Oncology

    The Department of Neurology and Interdisciplinary Neuro-oncology (Director: Prof. Ghazaleh Tabatabai) is a department covering both inpatient and outpatient clinical care... More information

  • Neural Dynamics and Magnetoencephalography

    The Department of Neural Dynamics and Magnetoencephalography was founded in the year 2020 and Prof. Dr. Markus Siegel was appointed head of the department. ...more information

  • Cellular Neurology

    Our research focus is on the cellular and molecular mechanisms of brain aging and age-related neurodegenerative diseases, with a special emphasis on the pathogenesis of Alzheimer´s disease and other cerebral proteopathies ...more information

  • Independent Research Groups

    The independent research groups at the HIH focus on a variety of research topics ...more information

Research groups

  • Ziemann Lab

    Brain Networks and Plasticity

    The human brain possesses the remarkable capacity of reorganization, which is the basis for adapting to constantly changing environmental conditions. This plasticity is of paramount importance ...more information

  • Himmelbach Lab

    Neuropsychology of Action

    The Research Group "Neuropsychology of Action" is dedicated to investigations of human action control. We study clinical impairments of action control and their neural substrates in patients with brain damage ...more information

  • Neher Lab

    Experimental Neuroimmunology

    An immune response is part of most neurological diseases, and the development of late-onset Alzheimer's Disease (AD) has been linked to immune related genes and most recently also to epigenetic modifications. ...more information

  • Gasser Lab

    Genetics of Parkinson's disease

    Parkinson's syndrome (PS) is the second most common neurodegenerative disease after Alzheimer's dementia. The vast majority of patients are ill with no apparent cause. ...more information

  • Laske Unit

    Dementia Research Unit

    The Dementia Research Unit is a clinical research unit of the Department of Cellular Neurology and the Department of Psychiatry. It closely collaborates with the outpatient Memory Clinic. ...more information

  • Weber Lab

    Clinical Genetics of Paroxysmal Neurological Diseases

    Paroxysmal neurological disorders include a broad spectrum of clinical entities such as migraine, episodic ataxia or myotonia. The research group is focussed on the clinical genetics ...more information

  • Ilg Lab

    Oculomotor Laboratory

    Playing video-games is a widely distributed leisure activity in our society. In order to estimate the consequences of video-game play, we study the details of eye movements and pupil light responses ... more information

  • Jucker Lab

    Experimental Neuropathology

    Cerebral proteopathy is a unifying term for cerebral neurodegenerative diseases in which aggregated proteins are abnormally deposited in the brain. The hallmark proteopathy is Alzheimer's disease (AD) ...more information

  • Mayer Lab

    Molecular Brain Development

    The mammalian neocortex is a highly complex and spatially heterogeneous structure, which has expanded significantly in mammalian evolution. Neocortical network function is at the heart of cognitive function ...more info

  • Kowarik Lab

    Neurological B cell Immunology

    The research group “Neurological B cell Immunology” is focused on the role of B cells in neuro-inflammatory diseases including multiple sclerosis (MS) and... more information

  • Siegel Lab

    Neural Dynamics and Magnetoencephalography

    The central goal of the laboratory is to investigate how cognition and behavior emerges from dynamic interactions across widely distributed neuronal ensembles... more information

  • Helfrich Lab

    Human Intracranial Cognitive Neurophysiology

    The goal of the Helfrich lab is to unravel the neural network mechanisms supporting higher cognitive functions  ...more info

  • Hedrich-Klimosch Lab

    Experimental Neurophysiology of Channelopathies

    Our research group uses transgenic mouse models to investigate the molecular mechanisms of disease-associated variants in genes encoding neuronal ion channels. ...more information

Research groups

  • Brockmann Lab

    Clinical Parkinson's Disease Research

    Parkinson's disease (PD) is the second most frequent neurodegenerative disorder after Alzheimer’s disease and affects about 1 to 2 % of individuals over the age of 65. The number is steadily increasing due to demographic changes in Western countries. ...more information

  • Kronenberg-Versteeg Unit

    Glia Biology Unit

    Glial cells are highly abundant in the mammalian brain, yet many questions regarding their development, function, and involvement in disease remain unanswered. ...more information

  • Naumann Lab

    Molecular Neurooncology

    Three to five of 100.000 people are annually diagnosed with a glioblastoma (GBM), the most malignant brain tumor in adults. Despite aggressive multimodal treatment including surgical resection and ...more information

  •  Unit

    Käser Unit

    Molecular Biomarkers Unit

    Processes related to Alzheimer ́s disease (AD) and other age-related neurodegenerative diseases start many years before the onset of the first clinical symptoms. At the moment of the first clinical complaints, the disease has already caused ...more information

  • Gasser Lab

    Dystonia

    Dystonia is the third most common movement disorder, and mutations in a growing number of genes have been identified as causes for hereditary forms in many cases. The aim of the group, which brings together clinical experience ...more information

  • Poli Lab

    Stroke and Neuroprotection

    The research focus of our Stroke and Neuroprotection Laboratory is to find new and to optimize existing neuroprotective strategies ...more information

  • Lerche Lab

    Experimental Epileptology

    Our research group is interested to unravel the mechanisms of well defined, mainly genetic, neurological, paroxysmal diseases, to understand correlations with clinical symptoms and to find new treatment options. ...more information

  • Hafed Lab

    Active Perception Lab

    Humans are tremendously reliant on the sense of vision to interact with their environment. Such interaction often involves the generation of motor outputs ...more information

  • Fitzgerald Lab

    Mitochondrial Biology of Parkinson’s Disease

    Neurodegenerative disorders are associated in a proportion of cases with genetic risk and gene mutations. However, the vast majority …more info

  • Grimm Lab

    Neuromuscular Imaging Group

    The group works on different projects concerning nerve imaging, particularly high-resolution ultrasound in neuromuscular disorders ...more information

  • Tabatabai Lab

    Laboratory for Clinical and Experimental Neuro-Oncology

    The Interdisciplinary Division of Neuro-Oncology at the Hertie-Institut for Clinical Brain Research is the result of the, in the context of the Excellent Initiative, newly created W3-Professorship in Neuro-Oncology ... more information

  • Kühn Lab

    Translational Imaging of Cortical Microstructure

    My Research Group uses translational MR imaging to understand how cortical microstructure links to human brain function in health and disease... more information

Research groups

  • Schöls Lab

    Section for Clinical Neurogenetics

    Neurogenetic diseases like cerebellar ataxia, hereditary spastic paraplegia and leukodystrophy are rare disorders. ...more information

  • Thier Lab

    Cognitive Neurology

    The lab addresses a variety of topics that, at first glance, may look disparate. Yet, there is a common denominator ...more information

  • Schüle Lab

    Genomic of Rare Movement Disorders

    Our group specializes in rare diseases. A disease is called rare, when it affects no more than 5 of 100,000 people. However, in the grand-scheme of things, rare diseases are not quite so rare ...more information

  • Giese Lab

    Section for Computational Sensomotorics

    The Section for Computational Sensomotorics investigates theoretical principles in the perception and control of motor actions. Research is organized around three main topics ...more information

  • Karnath Lab

    Section for Neuropsychology

    The Section for Neuropsychology focuses on the investigation of spatial cognition and object recognition in humans. The current issues of our work comprise the action control and sensorimotor coordination ...more information

  • Kahle Lab

    Functional Neurogenetics

    Age-related neurodegenerative diseases are a severe and increasingly worrisome burden for our aging population. Most of the chronic neurodegenerative diseases ...more information

  • Schwarz Lab

    Systems Neurophysiology Lab

    The overarching goal of our work is to understand the operating principles of the neocortex, a unique brain structure, which mainly evolved in mammals. There is clear evidence that the neocortex, in the broadest sense, endows the subject with cognitive capabilities. ...more information

  • Weiß Lab

    Deep Brain Stimulation

    The working group aims to uncover mechanisms of action of deep brain stimulation therapy and to translate the pathophysiological insights into future developments. …more information

  • Häufle Lab

    Motor Control Modeling

    The research group „Multi-Level Modeling in Motor Control and Rehabilitation Robotics“ focuses on the generation and control of active biological movements. We develop ...more information

  • Merk Lab

    Experimental Pediatric Neuro-Oncology

    Brain tumors are the leading cause of cancer-related deaths in infants, children, and adolescents. Our lab is mostly focusing on embryonal brain tumors including ... more information

  • Snaidero Lab

    Neuron-Glia Interactions

    The goal of the Snaidero lab is to decipher and control cellular interactions between neurons and glia cells in the cortex, focussing on the dynamic processes underlying myelination. ... more information

  • Renovanz Lab

    Health Care Research in Neuro-Oncology

    The group focuses on the health-related quality of life, psychosocial burden and unmet needs in neuro-oncological patients. Our key question is... more information

  • Synofzik Lab

    Translational Genomics of Neurodegenerative Diseases

    The translational research of our Research Division is fully geared by a systematic translational pipeline of developing therapy strategies for a broad range of genetically stratified neurodegenerative diseases ...more info

-HIH Lunch Seminar
The next HIH Lunch Seminar will take place on Monday, December 5, at 1pm via Zoom.

13:00 The prodromal stage of SPG4
Tim Rattay, Neurodegenerative Diseases, Group Schöls

13:30 Disentangling two movement-related predictive signals in the mouse brain: sensory gating vs. state estimation
Kalpana Gupta, Systemic Neuroscience, Group Schwarz

Zoom Details and Password: uwe.ilg@uni-tuebingen.de

Combining excellent research and patient care

Click on the image to watch the video