Neurology and Interdisciplinary Neuro-Oncology

The Department of Neurology and Interdisciplinary Neuro-oncology (Director: Prof. Ghazaleh Tabatabai) is a department covering both inpatient and outpatient clinical care. The scientific focus includes the entire spectrum of neuro-oncological diseaes and thus builds a bridge between the priority research foci oncology/immunology and neurosciences of the Medical Faculty Tübingen. The spectrum includes primary and metastatic tumors in the nervous system as well as neurological side effects of tumor therapies.

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Research Groups

Neuroonkologie

Tabatabai Lab

The projects of the lab are focusing on the biology of brain tumors, especially with targeted individualized therapies... more info

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Merk Lab

Brain tumors are the leading cause of cancer-related deaths in infants, children, and adolescents. Our lab is mostly focusing on embryonal brain tumors including ... more info

Neuroonkologie

Renovanz Lab

The group focuses on the health-related quality of life, psychosocial burden and unmet needs in neuro-oncological patients. Our key question is.... more info

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Sevenich Lab

Research in this lab is focused on tumor immunology in brain cancer in particular brain metastasis. ...more info

News

We would like to welcome you to our newsfeed.

August 2024

In the newly launched podcast‘Key To My Research, our Clinical Director Ms Ghazaleh Tabatabai talks about the topic ‘How intelligent are tumours?’

We bid farewell to our medical doctoral student Louise Maise on her Erasmus-funded semester abroad in Rome.

Hot-off the press. In the journal ‘Acta Neuropathologica Communications’ (IF.: 6.2) you will find the paper entitled‘Genome-wide CRISPR-Cas9 knockout screens identify DNMT1 as a druggable dependency in sonic hedgehog medulloblastoma’by our PhD student Foteini Tsiami on the role of DNMT1 in sonic hedgehog-altered medulloblastomas.
Congratulations to all involved especially Foteini and Daniel Merk.

July 2024

As part of the ‘Tübingen Therapy Symposium Neurooncology 2024’ on 31 July 2024, speakers from our specialist departments provided insights into recent cases, current findings, new clinical studies and therapeutic options.

The highlight of our exciting interdisciplinary programme were four contributions from our patients on the topics of glioblastoma, IDH-mutated glioma, meningeosis neoplastica and vestibular schwannoma.
They reported on their perspectives, attitudes and suggestions.

We would like to thank all contributors and speakers and the approximately 100 participants in the audience for this very enjoyable event.

The smooth running of the event would not have been possible without the support in front of and behind the scenes. We would like to sincerely thank Ms Gramer, Dr Dickreuter, Ms Pelz, Dr Rieger, Dr Becker, Mr Lang and Mr Wehle.



 
 
Finally out! ‘CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines’led by Dr Daniel Merk and our head Ghazaleh Tabatabai can be found in the journal Genome Medicine (IF.:10.4). Congratulations to all involved and happy reading!

AnnualDIAMOND meeting in Berlin. We look back on a lot of interaction between mentors and new contacts.



Our medical doctoral student Jil Trampert returns to the lab from her semester abroad in Marseille, reinvigorated and with lots of new ideas. We look forward to get back to work together!

 

June 2024

ASCO 2024 ‘Connect, collaborate and grow’ We are looking forward to all the interactions, meetings and discussions at this year's annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.
Many exciting contributions from the field of neuro-oncology.

On 19 June 2024, a ‘Post-ASCO’ meeting will take place in Tübingen with the relevant key messages.

May 2024

We congratulate our head of department, Ghazaleh Tabatabai on her election as spokesperson of the DFG Board for Neuroscience.

Another great seminar by Mrs Andrea Och on the topic of Networking Strategies.



 

April 2024

We are very happy about the successful defence of our former PhD student Bianca Walter, now finally Dr. rer. nat. Walter!
More information about her thesis with the name: ‘Understanding, inducing and exploiting actionable vulnerabilities in experimental glioma’




 

We are delighted about the seminar held by Prof. Thomas Schuhmacher as part of the DIAMOND programme on the topic of ‘Leadership and organisation in science and hospitals: managing complexity and effectiveness’. Many thanks for the organisation on site by Dr rer. nat. Sarah Erdmann.



March 2024

On World Women's Day, Prof Tabatabai and Prof Lisa Sevenich give exciting insights into their individual career paths.

We are overjoyed to publish our paper‘Functionally-instructed modifiers of response to ATR inhibition in experimental glioma’ in the ‘Journal of Experimental & Clinical Cancer Research’ (IP:11.3) with our first author Bianca Walter.

Further information, including a thread, can be found on LinkedIn and X.

We are excited about the start of the new DIAMOND cohort. Our colleagues, Jil Trampert, Surender Surender and Foteini Tsiami are looking forward to exciting seminars and the upcoming dates.

 

February 2024

We wish our medical doctoral student Jil Trampert a lot of fun in her Erasmus-funded semester abroad in Marseille.

 

January 2024


The newly published study on ‘Patient-reported outcomes’ using the TRACE app under the direction of Prof Renovanz can be found in the journal ‘Neuro-Oncology Practice’ - Many thanks to all co-authors.

 

December 2023

We warmly welcome University Professor Lisa Sevenich as newly appointed W2 Professor for ‘Experimental Neuro-Onco-Immunology’ in our department.



 
October 2023


We are pleased to welcome Ms Melissa Lang-Schnee for her lab rotation and bachelor thesis in our lab.

September 2023

At the annual meeting of the European Society of Neurooncology (EANO) in Rotterdam, we were able to gather valuable discussion about our projects in the poster session and the lecture session.

We are particularly pleased about the poster prize for Prof Mirjam Renovanz in the ‘Supportive care’ category on the results of the TRACE app, as well as the ‘selected abstract talk’ by Ms Foteini Tsiami on epigenetic regulators as a drug target in experimental sonic hedgehog medulloblastomas.

 

We are pleased about the great presentation of our medical doctoral students Ms Jil Trampert and Mr Felix Krautwurst at the IZKF mid-term colloquium.

We welcome Dr rer. nat. Sarah Erdmann, who will support us as a postdoctoral researcher from now on, especially in the ‘in vivo’ area as well as in science and laboratory management.

We look forward to working with her and wish her a pleasant start.

April 2023

We warmly welcome our new medical doctoral students Jil Trampert and Felix Krautwurst, who will be supporting us in the coming period. We wish them a pleasant and instructive start.

We are pleased to present a detailed and explanatory video regarding our publication ‘Clinical outcome of biomarker-guided therapies in adult patients with tumours of the nervous system.’

March 2023

We had an eventful and instructive time at the iFit Conference in Zell am See.
Bianca Walter and Dr Daniel Merk were able to present and discuss their current results.

 

We are pleased about the publication: ‘Clinical outcome of biomarker-guided therapies in adult patients with tumours of the nervous system.’ which was published in March in the journal Neurooncology Advances.

We warmly welcome our new colleague:Surender Surender will join us as a PhD student. We wish him an instructive and pleasant start.

January 2023

We welcome our new employees:

Mrs. Anke Jacob will support us from now on as a medical technical assistant, mainly in cell culture work.Ms. Bsc. Viktoria Dimanova will complete a laboratory rotation with us as part of her Master's degree in "Molecular Medicine".We wish both of them a pleasant start and look forward to working together.

December 2022

We wish you a Merry Christmas and a Happy New Year!We had a great Christmas party at the Hertie Institute and are happy about the distributed Christmas presents.

November 2022

Parts of our preclinical and clinical team will attend the annual meeting of the Society of Neurooncology (SNO) (16.11-20.11.2022).

 

 

DirectorDepartment of Neurology and Interdisciplinary Neuro-Oncology
Prof. Dr. Dr. Ghazaleh TabatabaiPhone 07071 29-85018ghazaleh.tabatabai@uni-tuebingen.deAddress

Hertie Center of Neurology
Hertie Institute for Clinical Brain Research
Department of Neurology & Interdisciplinary Neuro-Oncology

Otfried-Müller-Straße 27
72076 Tübingen

Phone: +49 (0)7071 29-85018
Fax: +49 (0)7071 29-5957

Office

Office
Phone: +49 (0)7071 29-83269

General information

Research