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Laying the foundations for tomorrow's medicine

News

  • First specific drug therapy for a severe early form of epilepsy

    Researchers from Tübingen led by Dr. Ulrike Hedrich-Klimosch, Dr. Stephan Lauxmann and Prof. Dr. Holger Lerche from the HIH, the University Hospital and the University of Tübingen have now used a drug for the first time that is actually approved for the treatment of multiple sclerosis.

    See Press Release

  • Isabel Gugel receives Margarete von Wrangell Fellowship

    Dr. Isabel Gugel is the first (neuro)surgeon to be accepted into the “Margarete von Wrangell” program. The fellowship allows her to further build up her scientific profile and to qualify for the appointment to a professorship.

    ... more information

  • Quantum sensors enable painless muscle diagnostics for the first time

    They could partially replace the current standard method and revolutionize muscle diagnostics, reports a research team led by Justus Marquetand.

    Press release (in German only)

  • A stressed mind

    Feeling permanently stressed by COVID-19? The pandemic has upset our daily rhythms. But how does stress affect our brains? Dr. Mondino investigates this question in the latest video by the Hertie Foundation.

    Link to the video

  • Perception of dynamic facial expressions: Why the brain is (still) superior to the computer

    Our brain processes facial expressions independently of the face shape - which allows us to even understand the emotions of fantasy figures like Master Yoda.

    Read the press release (in German only)

  • "What has been approved in the U.S. is something completely new"

    Last Monday, the U.S. Food and Drug Administration (FDA) approved the Alzheimer's drug aducanumab, using its "accelerated approval" program. Prof. Dr. Mathias Jucker talks about the drug with the Hertie Foundation (interview in German only).

Departments

  • Neurology and Stroke

    The Department of Neurology and Stroke has the main focuses in neurovascular medicine (vessel diseases of the brain, cerebral stroke), neuro-oncology (brain tumors, brain metastases), neuro-immunology (e.g., multiple sclerosis) and neuro-intensive medicine. ...more information

  • Neurodegenerative Diseases

    The Department of Neurodegenerative Diseases treats in-patients on a ward of about 20 beds and in several out-patient clinics. The clinical focus lies on neurodegenerative diseases such as Parkinson’s disease, the ataxias, spastic paraplegias, and dementias. ...more information

  • Neurology and Epileptology

    The Department of Neurology and Epileptology has a focus on epilepsy and other paroxysmal neurological disorders. In these diseases, the excitability of nerve cells temporarily changes either due to genetic or acquired defects. ...more information

  • Department of Neurology and Interdisciplinary Neuro-Oncology

    The Department of Neurology and Interdisciplinary Neuro-Oncology became the HIH's sixth department in 2020 with Prof. Dr. Dr. Ghazaleh Tabatabai as the first woman among the directors ...more information

  • Neural Dynamics and Magnetoencephalography

    The Department of Neural Dynamics and Magnetoencephalography was founded in the year 2020 and Prof. Dr. Markus Siegel was appointed head of the department. ...more information

  • Cellular Neurology

    Our research focus is on the cellular and molecular mechanisms of brain aging and age-related neurodegenerative diseases, with a special emphasis on the pathogenesis of Alzheimer´s disease and other cerebral proteopathies ...more information

  • Independent Research Groups

    The independent research groups at the HIH focus on a variety of research topics ...more information

Research groups

  • Neurology and Stroke

    Brain Networks and Plasticity

    The human brain possesses the remarkable capacity of reorganization, which is the basis for adapting to constantly changing environmental conditions. This plasticity is of paramount importance ...more information

  • Independent Research Group

    Neuropsychology of Action

    The Research Group "Neuropsychology of Action" is dedicated to investigations of human action control. We study clinical impairments of action control and their neural substrates in patients with brain damage ...more information

  • Cellular Neurology

    Experimental Neuroimmunology

    An immune response is part of most neurological diseases, and the development of late-onset Alzheimer's Disease (AD) has been linked to immune related genes and most recently also to epigenetic modifications. ...more information

  • Neurodegenerative Diseases

    Genetics of Parkinson's disease

    Parkinson's syndrome (PS) is the second most common neurodegenerative disease after Alzheimer's dementia. The vast majority of patients are ill with no apparent cause. ...more information

  • Cellular Neurology

    Dementia Research Unit

    The Dementia Research Unit is a clinical research unit of the Department of Cellular Neurology and the Department of Psychiatry. It closely collaborates with the outpatient Memory Clinic. ...more information

  • Neurology and Epileptology

    Clinical Genetics of Paroxysmal Neurological Diseases

    Paroxysmal neurological disorders include a broad spectrum of clinical entities such as migraine, episodic ataxia or myotonia. The research group is focussed on the clinical genetics ...more information

  • Independent Research Group

    Oculomotor Laboratory

    Playing video-games is a widely distributed leisure activity in our society. In order to estimate the consequences of video-game play, we study the details of eye movements and pupil light responses ... more information

  • Cellular Neurology

    Experimental Neuropathology

    Cerebral proteopathy is a unifying term for cerebral neurodegenerative diseases in which aggregated proteins are abnormally deposited in the brain. The hallmark proteopathy is Alzheimer's disease (AD) ...more information

  • Independent Research Group

    Molecular Brain Development

    The mammalian neocortex is a highly complex and spatially heterogeneous structure, which has expanded significantly in mammalian evolution. Neocortical network function is at the heart of cognitive function ...more info

  • Neurology and Stroke

    Neurological B cell Immunology

    The research group “Neurological B cell Immunology” is focused on the role of B cells in neuro-inflammatory diseases including multiple sclerosis (MS) and... more information

  • Neural Dynamics and Magnetoencephalography

    Neural Dynamics and Magnetoencephalography

    The central goal of the laboratory is to investigate how cognition and behavior emerges from dynamic interactions across widely distributed neuronal ensembles... more information

  • Independent Research Group

    Human Intracranial Cognitive Neurophysiology

    The goal of the Helfrich lab is to unravel the neural network mechanisms supporting higher cognitive functions  ...more info

Research groups

  • Neurodegenerative Diseases

    Clinical Parkinson's Disease Research

    Parkinson's disease (PD) is the second most frequent neurodegenerative disorder after Alzheimer’s disease and affects about 1 to 2 % of individuals over the age of 65. The number is steadily increasing due to demographic changes in Western countries. ...more information

  • Cellular Neurology

    Glia Biology Unit

    Glial cells are highly abundant in the mammalian brain, yet many questions regarding their development, function, and involvement in disease remain unanswered. ...more information

  • Neurology and Stroke

    Molecular Neurooncology

    Three to five of 100.000 people are annually diagnosed with a glioblastoma (GBM), the most malignant brain tumor in adults. Despite aggressive multimodal treatment including surgical resection and ...more information

  •  Unit

    Cellular Neurology

    Molecular Biomarkers Unit

    Processes related to Alzheimer ́s disease (AD) and other age-related neurodegenerative diseases start many years before the onset of the first clinical symptoms. At the moment of the first clinical complaints, the disease has already caused ...more information

  • Neurology and Epileptology

    Translational Imaging

    The focus of our research group is the structural and functional imaging of neurological diseases with a particular focus on epileptology. We use multi-modal imaging techniques to improve the understanding of disease development ...more information

  • Neurodegenerative Diseases

    Dystonia

    Dystonia is the third most common movement disorder, and mutations in a growing number of genes have been identified as causes for hereditary forms in many cases. The aim of the group, which brings together clinical experience ...more information

  • Neurology and Stroke

    Neurophonetics and Translational Neurorehabilitation

    The work group Neurophonetics and Translational Neurorehabilitation is based on a cooperation between the University of Tübingen and a neurological rehabilitation clinic (Fachkliniken Hohenurach). ...more information

  • Neurology and Stroke

    Stroke and Neuroprotection

    The research focus of our Stroke and Neuroprotection Laboratory is to find new and to optimize existing neuroprotective strategies ...more information

  • Neurology and Epileptology

    Experimental Epileptology

    Our research group is interested to unravel the mechanisms of well defined, mainly genetic, neurological, paroxysmal diseases, to understand correlations with clinical symptoms and to find new treatment options. ...more information

  • Independent Research Group

    Active Perception Lab

    Humans are tremendously reliant on the sense of vision to interact with their environment. Such interaction often involves the generation of motor outputs ...more information

  • Neurodegenerative Diseases

    Mitochondrial Biology of Parkinson’s Disease

    Neurodegenerative disorders are associated in a proportion of cases with genetic risk and gene mutations. However, the vast majority …more info

  • Neurology and Epileptology

    Neuromuscular Imaging Group

    The group works on different projects concerning nerve imaging, particularly high-resolution ultrasound in neuromuscular disorders ...more information

  • Neuro-Oncology

    Laboratory for Clinical and Experimental Neuro-Oncology

    The Interdisciplinary Division of Neuro-Oncology at the Hertie-Institut for Clinical Brain Research is the result of the, in the context of the Excellent Initiative, newly created W3-Professorship in Neuro-Oncology ... more information

Research groups

  • Neurology and Epileptology

    Migraines and Primary Headache Disorders

    Our group aims at unraveling the molecular pathophysiology of migraine and other primary headache disorders. ...more information

  • Neurodegenerative Diseases

    Section for Clinical Neurogenetics

    Neurogenetic diseases like cerebellar ataxia, hereditary spastic paraplegia and leukodystrophy are rare disorders. ...more information

  • Independent Research Group

    Cognitive Neurology

    The lab addresses a variety of topics that, at first glance, may look disparate. Yet, there is a common denominator ...more information

  • Neurodegenerative Diseases

    Genomic of Rare Movement Disorders

    Our group specializes in rare diseases. A disease is called rare, when it affects no more than 5 of 100,000 people. However, in the grand-scheme of things, rare diseases are not quite so rare ...more information

  • Independent Research Group

    Section for Computational Sensomotorics

    The Section for Computational Sensomotorics investigates theoretical principles in the perception and control of motor actions. Research is organized around three main topics ...more information

  • Independent Research Group

    Section for Neuropsychology

    The Section for Neuropsychology focuses on the investigation of spatial cognition and object recognition in humans. The current issues of our work comprise the action control and sensorimotor coordination ...more information

  • Neurodegenerative Diseases

    Functional Neurogenetics

    Age-related neurodegenerative diseases are a severe and increasingly worrisome burden for our aging population. Most of the chronic neurodegenerative diseases ...more information

  • Independent Research Group

    Systems Neurophysiology Lab

    The overarching goal of our work is to understand the operating principles of the neocortex, a unique brain structure, which mainly evolved in mammals. There is clear evidence that the neocortex, in the broadest sense, endows the subject with cognitive capabilities. ...more information

  • Neurodegenerative Diseases

    Deep Brain Stimulation

    The working group aims to uncover mechanisms of action of deep brain stimulation therapy and to translate the pathophysiological insights into future developments. …more information

  • Independent Research Group

    Motor Control Modeling

    The research group „Multi-Level Modeling in Motor Control and Rehabilitation Robotics“ focuses on the generation and control of active biological movements. We develop ...more information

  • Neuro-Oncology

    Experimental Pediatric Neuro-Oncology

    Brain tumors are the leading cause of cancer-related deaths in infants, children, and adolescents. Our lab is mostly focusing on embryonal brain tumors including ... more information

  • Independent Research Group

    Neuron-Glia Interactions

    The goal of the Snaidero lab is to decipher and control cellular interactions between neurons and glia cells in the cortex, focussing on the dynamic processes underlying myelination. ... more information

-Genetic epilepsies and other neuronal ion channel disorders: Mechanisms and therapeutic perspectives
September 22 – September 24, 2021

Location: University Hospital Tübingen, CRONA, Hoppe-Seyler-Str. 3, 71076 Tübingen
Room: 210 (lecture hall)
as well as virtual
-HIH Lunch Seminar
The next HIH Lunch Seminar will take place on Monday, Ocotber 4 2021, at 1pm via Zoom.

13:00 Saccade properties under monocular and binocular viewing
Jana Bay, Systemic Neuroscience, Group Ilg

13:30 Computational models for complex motor skills in patients with neurodegenerative and neurodevelopmental disorders
Jana Lang, Systemic Neuroscience, Group Giese

Zoom-Details and Password: uwe.ilg@uni-tuebingen.de
-Defense PhD thesis of Linda Oberle (Dept. Jucker)
Topic: Mechanism of neuronal dysfunction in Sepsis-induced Cognitive Impairment
Location: Conference room DZNE

Combining excellent research and patient care

Click on the image to watch the video