Dr. Alexandro Ruíz Requelme
PostDoc until 2021 Now: Assistant professor, University of Santiago de Compostela, Spain
Melanie Barth, PhD
PhD student until 2021 Now:…
Alumni
Dr. Alexandro Ruíz Requelme
PostDoc until 2021 Now: Assistant professor, University of Santiago de Compostela, Spain
Melanie Barth, PhD
PhD student until…
Our research focus is on the cellular and molecular mechanisms of brain aging and age-related neurodegenerative diseases, with a special emphasis on the pathogenesis of Alzheimer´s disease and other…
Molecular biomarkers have become indispensable tools not only for the diagnosis and stratification of patients with neurodegenerative diseases such as Alzheimer’s disease (AD), but also for…
In the Neuroimmunology group, we have recently found that microglia are capable of "remembering" inflammatory insults, i.e. microglia show adaption of their immune responses to subsequent stimuli…
1. To investigate how peripheral inflammatory stimuli affect the brain's immune response, how they induce innate immune memory in the brain, and how immune memory affects neurodegenerative…
Menden K et al. (2023) A multi-omics dataset for the analysis of frontotemporal dementia genetic subtypes. Sci Data 10(1):849 (Abstract)
Pantazis CB et al. (2022) A reference induced…
Given the crucial role of microglia in development, brain homeostasis, aging and disease, there is a growing need for human(ized) screening tools and disease models to aid in the search for new…
1. To understand the role of glia & glial genetic risk genes in cerebral proteopathies.
2. To investigate brain immune interactions to delineate how glia contribute to neuronal…
Hofmann A, Häsler LM, Lambert M, Kaeser SA, Gräber-Sultan S, Obermüller U, Kuder-Buletta E, la Fougere C, Laske C, Vöglein J, Levin J, Fox NC, Ryan NS, Zetterberg H, Llibre-Guerra JJ, Perrin RJ,…